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Demerol (meperidine) is an opioid pain medication. A drug used to treat moderate to severe pain. It binds to opioid receptors in the central nervous system. Demerol is a type of analgesic agent and a type of opioid. Also called meperidine hydrochloride. Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class. DEMEROL is indicated for the relief of acute episodes of moderate to severe pain. An opioid is sometimes called a narcotic. Demerol, is a white crystalline substance with a melting point of 186° C to 189° C. It is readily soluble in water and has a neutral reaction and a slightly bitter taste. The solution is not decomposed by a short period of boiling. Demerol is used to relieve moderate to severe pain. It may also be used before and during surgery or other medical procedures. Demerol injection is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the body senses pain. The tablets contain 50 mg or 100 mg of DEMEROL brand of meperidine hydrochloride. Demerol comes in tablet or liquid forms. The tablets are circular in shape, white in color and come in 50 mg or 100 mg strengths. As a liquid, Demerol comes in a syrup or as an injectable solution; however, the injectable form is typically only administered by medical professionals. When used as prescribed, Demerol tablets and syrup are taken orally. Demerol is a drug used to treat moderate to severe pain. It binds to opioid receptors in the central nervous system. Demerol is a type of analgesic agent and a type of opioid. DEMEROL (meperidine hydrochloride, USP) Tablet and Oral Solution are opioid agonists. DEMEROL Tablets are available as 50 mg and 100 mg Tablets for oral administration. Demerol is the brand name for an injectable form of meperidine, an opioid painkiller that is also referred to as pethidine. Classified as a narcotic analgesic, the drug is used to treat moderate to severe pain, with effects similar to morphine or oxycodone. DEMEROL Tablets and Oral Solution a Buy Demerol Onlinere indicated for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Demerol is a strong pain medicine that is used to manage the relief short-term pain, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them. Meperidine is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. It belongs to the group of medicines called narcotic analgesics (pain medicines). Meperidine acts on the central nervous system (CNS) to relieve pain. This medicine should not be used to relieve chronic (long-lasting or recurrent) pain. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Buy Demerol Pills Online
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Demerol Dosage and Administration
The usual adult dose of meperidine is 50 mg to 150 mg taken every 3 to 4 hours, as prescribed by the doctor and as necessary for pain.
The dose for seniors should be reduced to reduce the potential for adverse effects. Buy Pain Pills Online
This medication may be habit-forming if taken for extended periods of time. It should not be used for longer than 2 days. Do not take this medication in higher doses or for a longer period of time than prescribed by your doctor.
Doses should not exceed 600 mg/24hr; oral route is not recommended for treatment of acute or chronic pain
Pain: 50-150 mg PO/IM/SC every 4hr PRN; adjust dose based degree of response. (PO= per os, IM= intra muscular, SC= sub cutaneous, PRN=when necessary).
Preoperatively: 50-100 mg IM/SC 30-90 min before beginning anesthesia
Continuous infusion: 15-35 mg/hr
Obstetrical analgesia: 50-100 mg IM/SC; repeated q1-3hr PRN.
Demerol forms and strength
Tablet form: 50 mg to 100 mg
Syrup form: 50 mg/5 ml
Injectable solution form: 25 mg/ml, 50 mg/ml, 75 mg/ml, 100mg/ml
Intravenous (IV) injection: inject the dose of 10 mg/ml slowly. Injection should be considered only when opiate antagonist and administration of oxygen and respiratory monitoring facilities are available.
selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, concomitant disease or other drug therapy While subcutaneous administration is suitable for occasional use, intramuscular administration is preferred when repeated doses are required. If intravenous administration is required, dosage should be decreased and the injection made very slowly, preferably utilizing a diluted solution.
Adolescents and Children
1.1 to 1.8 mg/kg (Maximum 150 mg/dose) orally every 3 to 4 hours as needed.
Adults: The usual dosage is 50 mg to 150 mg intramuscularly or subcutaneously every 3 or 4 hours as needed for pain. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely.
Children: The usual dosage is 0.5 mg/lb to 0.8 mg/lb intramuscularly or subcutaneously up to the adult dose, every 3 or 4 hours as necessary. Do not stop DEMEROL Tablets or Oral Solution abruptly in a physically
dependent patient. Renal impairment: Avoid use
Hepatic impairment: Consider lower initial dose initially; increased opioid effect possible in cirrhosis.
Demerol Side Effects
Along with its needed effects, Demerol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur, they may need medical attention. These include;
Nausea, vomiting, constipation, dry mouth, flushing, sweating, lightheadedness, dizziness, Agitation, chest pain or discomfort, confusion, decrease in the frequency of urination, blurred vision, difficult or troubled breathing, cold, clammy skin, cough, darkening of the skin, decrease in urine volume, diarrhea, difficulty with swallowing, difficulty in passing urine (dribbling), drowsiness, and pain/redness at the injection site may occur. To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative. If any of these effects persist, consult your doctor. Buy Demerol Pills Online
lightheadedness, dizziness, sedation, nausea, vomiting, sweating, constipation, loss of appetite, headache, weakness, dry mouth, itching, urinating less than usual, flushing, drowsiness, or loss of interest in sex. Buy Demerol Pills Online
To prevent constipation, eat dietary fiber, drink enough water, and exercise. You may also need to take a laxative. Ask your pharmacist which type of laxative is right for you.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Dererol is contraindicated in the following patients;
1 Patients with suspected surgical abdomen (e.g., acute appendicitis or pancreatitis).
2 Patients with mild pain that can be managed with other pain medications.
3 Meperidine is contraindicated in patients that are actively receiving or have been exposed during the past 14 days to monoamine oxidase inhibitors (MAOI) because of unpredictable severe, and occasionally fatal reactions such as coma, severe respiratory depression, hypotension, cyanosis, and acute narcotic overdose.
4 Patients with acute alcoholism, delirium tremens, and convulsive disorders.
5 Patients with severe CNS depression, increased cerebrospinal or intracranial pressure,
and head injury.
-Demerol is contraindicated in patients with hypersensitivity to Demerol.
-Demerol is contraindicated in patients who are receiving monoamine oxidase (MAO) inhibitors or those who have recently received such agents. Therapeutic doses of Demerol have occasionally precipitated unpredictable, severe, and occasionally fatal reactions in patients who have received such agents within 14 days.
Do not take meperidine if you:
are allergic to meperidine or any ingredients of the medication
are experiencing acute alcoholism or delirium tremens
are experiencing acute asthma or other obstructive airway disease
are experiencing acute respiratory depression
have abnormal heart rhythms
have a blockage of the gastrointestinal tract, particularly paralytic ileus
have convulsive (seizure) disorders
have cor pulmonale
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Demerol Warnings and Precautions
Before taking meperidine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. There is a high risk of opioid addiction, abuse, and misuse, which can lead to overdose and death; assess each patient’s risk prior to prescribing and monitor all patients regularly for the development of these behaviors or conditions; Serious, life-threatening, or fatal respiratory depression may occur. Monitor for respiratory depression, especially during initiation or following a dose increase.
Prolonged use of DEMEROL Injection during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. If prolonged opioid use is required in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available. Talk to your pharmacist for more details. Buy Demerol Pills Online
Demerol should not be used for treatment of chronic pain. Demerol (Meperidine) should only be used in
the treatment of acute episodes of moderate to severe pain. Prolonged meperidine use may increase the risk of toxicity (e.g. seizures) from the accumulation of the meperidine metabolite, normeperidine.
Meperidine is usually used only for a short time. Repeated or high doses may cause drug levels to build up in the body and cause serious side effects such as seizures and shaking. Caution is advised if this medication is used for conditions that require long-term or high-dosage treatment (such as sickle cell anemia, burns, cancer). Consult your doctor or pharmacist for details.
Use of Demerol may be associated with increased potential risks and should be used with caution in the following conditions:
-sickle cell anemia,
-adrenocortical insufficiency (e.g. Addison’s disease);
-CNS (Central Nervous System) depression or coma;
-kyphoscoliosis associated with respiratory depression;
-myxedema or hypothyroidism;
-prostatic hypertrophy or urethral stricture;
-severe impairment of hepatic,
-pulmonary, or renal function; and toxic psychosis.
Before taking meperidine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
The administration of meperidine (Addison’s disease) may obscure the diagnosis or clinical course in patients with acute abdominal conditions. see wiki