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Dosage form and strength
SUBUTEX sublingual tablet is supplied as an uncoated oval white tablet in two dosage strengths:
buprenorphine 2 mg, and buprenorphine 8 mg
Treatment with Subutex sublingual tablets is intended for use in adults and children aged 16 years or over who have agreed to be treated for opioid dependence.
The initial dose is from 0.8mg to 4mg, administered as a single daily dose. Administer SUBUTEX sublingually as a single daily dose.
The dose of Subutex should be increased progressively according to the clinical effect of the individual patient and should not exceed a maximum single daily dose of 32mg. The dosage is titrated according to reassessment of the clinical and psychological status of the patient.
Administration is sublingual. The sublingual route is the only effective and safe route of administration for this drug. Subutex tablet should be kept under the tongue until dissolved, which usually occurs within 5 to 10 minutes.
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The initial recommended Subutex dose or Subutex dosage ranges from 0.8 mg to 4 mg, taken once a day. Then, the Subutex dosage can increase based on the effects of the drug, but this should be done under close clinical supervision. It is not recommended that anyone exceed a daily Subutex dose of more than 32 mg.
Then, the Subutex dosage can gradually be reduced over time and eventually stopped altogether. Buy Subutex Online
It is important that as a person’s Subutex dosage is being decreased that they are monitored to help prevent the potential for relapse.
– Do not take Subutex more often than prescribed by your doctor.
– If you are prescribed a dose of 2 or more Subutex tablets at the same time:
– Ask your doctor for instructions on the right way to take Subutex tablets
– Follow the same instructions every time you take a dose of Subutex tablet
-Put the tablets under your tongue. Let them dissolve completely. Buy Subutex Online
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Some of the common short-term Subutex side effects can include back pain, constipation, hoarseness of the voice, nausea, painful urination, headache, sleep problems, vomiting, bloating or swelling of the face, arms, hands, lower legs, or feet; bloody or cloudy urine, Bladder pain, cough producing mucus, blurred vision, difficulty breathing, feeling lightheaded or dizzy, diarrhea, flushing of the skin or sweating. Constipation (incomplete or hard bowel movements) is a very common side effect of all opioid medicines. Talk to your doctor about the use of laxatives (medicines to treat constipation) and stool softeners to prevent or treat constipation while using Subutex. These are not all the possible side effects of Subutex. For a complete list, consult your doctor or pharmacist.
– Drug withdrawal syndrome
– Numb mouth
– Decrease in sleep (insomnia)
– Blurred vision
– Back pain
Tell your doctor about any side effect that bothers you or that does not go away. More from Wikipedia
- Subutex is contraindicated in patients who are hypersensitive to buprenorphine or any other component of the tablet.
- Subutex is contraindicated in patients suffering from Severe respiratory insufficiency.
- Subutex is contraindicated in Children less than 16 years of age.
- Subutex is contraindicated in patients suffering from cute alcoholism or delirium tremens.
- Subutex is contraindicated in patients suffering from severe hepatic insufficiency.
- Subutex is contraindicated in Breast feeding mothers.
Do not take Subutex if you are allergic to buprenorphine or naloxone.
Children less than 16 years of age
Severe respiratory insufficiency
Severe hepatic insufficiency
Acute alcoholism or delirium tremens
WARNINGS AND PRECAUTIONS
- Store Subutex safely out of the sight and reach of children. Buprenorphine can cause severe, possibly fatal, respiratory depression in children.
- Concomitant use of Subutex or other CNS depressants increases the risk of adverse reactions including overdose and death.
- Subutex has been associated with life-threating respiratory depression and death.
- Subutex contains buprenorphine, a Schedule III controlled substance that can be abused.
- Risk of Overdose in Opioid-Naïve Patients: Subutex is NOT appropriate as an analgesic. There have been reported deaths of opioid naïve individuals who received a 2 mg sublingual dose of buprenorphine.
- Caution patients about driving or operating hazardous machinery until they are reasonably certain that buprenorphine therapy does not adversely affect his or her ability to engage in such activities. Like other opioids, Subutex may produce orthostatic hypotension in ambulatory patients. Buy Subutex Online
Subutex may not be right for you. Before taking Subutex, tell your doctor if you:
– Have liver or kidney problems
– Have a head injury or brain problem
– Have problems urinating
– Have gallbladder problems
– Have adrenal gland problems